SIGNIFICANCE OF BRACHYTHERAPY TREATMENT IN ADVANCED CANCER OF TRANSVERSE COLON (CASE REPORT)

Authors

  • Hanna FEDORENKO Region Oncology Hospital, Kyiv, Ukraine
  • Serhiy ROMANENKO Region Oncology Hospital, Kyiv, Ukraine
  • Oksana KOZAK Region Oncology Hospital, Kyiv, Ukraine
  • Lyidmila ROMANENKO Region Oncology Hospital, Kyiv, Ukraine
  • Hanna FEDORENKO Region Oncology Hospital, Kyiv, Ukraine

DOI:

https://doi.org/10.17721/3041-1491/2024.11-12

Keywords:

brachytherapy, transverse colon cancer, metastasis, intratissue irradiation

Abstract

Introduction. Colorectal cancer, including cancer of the transverse colon, is known for its potential to metastasize to distant organs. Although the liver and lungs are common metastatic sites, metastasis to the vagina is rare and poses unique challenges for treatment.

Methods. This case report details a rare instance of vaginal metastasis in a 58-year-old patient with advanced transverse colon adenocarcinoma. According to our experience, intracavitary brachytherapy of metastasis into the vagina is not effective, especially in cases of volumetric tumors.

Results. As a rule, we use interstitial brachytherapy with an intracavitary applicator of maximal diameter. Over a 24-month follow-up period, there was no local recurrence or progression of the disease, along with improved quality of life for the patient.

Conclusions. This case highlights the importance of personalized treatment approaches and underscores the need for further research to optimize brachytherapy protocols for the effective treatment of rare metastatic sites in colorectal cancer.  

 

References

Kwon, S.K., Yu, C.S., Lee, S.W., Kim, J., Song, I., Lee, J.L., Kim, C.W., Yoon, Y.S., Park, I.J., Lim, S.B., & Kim, J.C. (2020). Isolated vaginal metastasis from stage I colon cancer: A case report. World J. Clin. Cases, 8(3), 527–534. https://doi.org/10.12998/wjcc.v8.i3.527

 

Marchal, F., Leroux, A., Hoffstetter S., & Granger P. (2006). Vaginal metastasis revealing colon adenocarcinoma. Int. J. Colorectal. Dis., 21, 861–862. https://doi.org/10.1007/s00384-004-0734-x

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Published

2025-01-26

How to Cite

FEDORENKO, H. ., ROMANENKO, S. ., KOZAK, O., ROMANENKO, L. ., & FEDORENKO, H. . (2025). SIGNIFICANCE OF BRACHYTHERAPY TREATMENT IN ADVANCED CANCER OF TRANSVERSE COLON (CASE REPORT). The Conference Proceedings “Medical Physics – the Current Status, Problems, the Way of Development. Innovation technologies”, 1(1), 105-109. https://doi.org/10.17721/3041-1491/2024.11-12